3-Chloro-4-hydroxyphenylboronic acid

3-Chloro-4-hydroxyphenylboronic acid - Names and Identifiers

Name	3-Chloro-4-hydroxyphenylboronic acid
Synonyms	4-Borono-2-chlorophenol (3-Chloro-4-hydroxyphenyl) 3-Chloro-4-hydroxyphenylboronic acid 3-Chloro-4-hydroxybenzeneboronic acid (3-Chloro-4-hydroxyphenyl)boronic acid B-(3-chloro-4-hydroxy-phenyl)boronic acid Boronic acid, B-(3-chloro-4-hydroxyphenyl)- boronic acid, B-(3-chloro-4-hydroxyphenyl)- 3-Chloro-4-hydroxyphenylboronic Acid (contains varying amounts of Anhydride)
CAS	182344-13-4
InChI	InChI=1/C6H6BClO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9-11H

3-Chloro-4-hydroxyphenylboronic acid - Physico-chemical Properties

Molecular Formula	C6H6BClO3
Molar Mass	172.37
Density	1.49g/cm³
Melting Point	223-228°C
Boling Point	360.6°C at 760 mmHg
Flash Point	171.9°C
Vapor Presure	7.91E-06mmHg at 25°C
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.602
Physical and Chemical Properties	Storage Conditions: Keep Cold

3-Chloro-4-hydroxyphenylboronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT, KEEP COLD

3-Chloro-4-hydroxyphenylboronic acid - Introduction

acid, the chemical formula is C6H5BClO2, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: acid is a white crystalline solid.
2. Chemical properties: It is an acidic compound that can be dissolved in water. It is a relatively stable compound, but it will decompose under the action of high temperature or oxidant.

Use:
1. Chemical Synthesis: acid is commonly used as a reagent for organic synthesis reactions, especially for copper-catalyzed aryl substitution reactions.
2. Drug research: It is widely used in the biomedical field and can be used as an intermediate for the preparation of drugs.
3. Coordination chemistry: acid can be used as a ligand for metal ions to prepare coordination compounds.

Method:
There are two main methods for preparing acid:
1. Arylborane compounds are obtained by reacting with alkyl halides. Arylboranes and bromoalkanes are usually used to react under Copper catalysis to obtain arylboranes.
2. Aromatic carbonyl compounds are obtained by reacting with nucleophile boric acid. For example, P-Hydroxybenzoic acid reacts with triphenylborane to produce acid.

Safety Information:
1. acid belongs to chemicals, please follow the relevant safety procedures, avoid direct contact with skin and eyes.
2. With other chemicals such as strong oxidants and strong acids should be stored separately to avoid dangerous chemical reactions.
3. Wear appropriate personal protective equipment such as gloves, goggles and lab coats during use.
4. In case of accidental contact or accidental application, please clean the affected area immediately and seek medical help.

Last Update：2024-04-09 15:17:54